Pathological characterization of pachydermia in pachydermoperiostosis
نویسندگان
چکیده
منابع مشابه
Pathological characterization of pachydermia in pachydermoperiostosis
Pachydermoperiostosis is a rare hereditary disease, which presents with the cutaneous manifestations of pachydermia and cutis verticis gyrata. Histological findings in pachydermia frequently include dermal edema, mucin deposition, elastic fiber degeneration, dermal fibrosis and adnexal hyperplasia. However, the severity of these findings varies between clinical reports, and a systematic multipl...
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Dear Editor, Pachydermoperiostosis (PDP; Online Mendelian Inheritance in Man #614441) is a rare hereditary disease characterized by distinctive digital clubbing, periostosis and pachydermia. Patients with PDP harbor homozygous mutations in the solute carrier organic anion transporter family member 2A1 gene (SLCO2A1) or the 15-hydroxyprostaglandin dehydrogenase gene (HPGD), resulting in elevated...
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To cite: Chakraborty PP, Bhattacharjee R, Mukhopadhyay S, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016214624 DESCRIPTION A 19-year-old male patient presented with a yearlong history of progressive painful enlargement of his hands and feet associated with excessive sweating and greasiness of the face, palms and soles. He also noticed pain over his wr...
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Introduction Pachydermoperiostosis is a syndrome characterized by finger clubbing, periosteal new bone formation especially over the distal ends of long bones, and coarsening of the facial features, with thickening, furrowing and oiliness of the skin of the face and forehead. The first reported cases were the Hagner brothers, who had typical features of this syndrome. They were first described ...
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Context Acromegaly usually is suspected on clinical grounds. Biochemical confirmation is required to optimize therapy, but there are other differential diagnoses. Case Description We describe a 24-year-old Uzbek man who presented with many clinical symptoms and signs of apparent acromegaly. On examination, the patient showed a rugose folding of his scalp, with the formation of tender, painful...
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ژورنال
عنوان ژورنال: The Journal of Dermatology
سال: 2015
ISSN: 0385-2407,1346-8138
DOI: 10.1111/1346-8138.12869